Reviewed by Dr. Elena Vance, DOLast reviewed 4 sources cited
Quick Summary
Saxenda (liraglutide) and Victoza (liraglutide) are both glp-1 receptor agonists. In clinical trials, Saxenda showed greater weight loss (8% vs 3.2%).
See the comparison table below for detailed side-by-side data.
Saxenda vs Victoza: Full Comparison
| Feature | Saxenda(liraglutide) | Victoza(liraglutide) |
|---|---|---|
| Active Ingredient | liraglutide | liraglutide |
| Drug Class | GLP-1 receptor agonist | GLP-1 receptor agonist |
| Manufacturer | Novo Nordisk | Novo Nordisk |
| FDA Approved | 2014-12-23 | 2010-01-25 |
| Approved Indications |
|
|
| Route | subcutaneous injection | subcutaneous injection |
| Frequency | Once daily | Once daily |
| Starting Dose | 0.6 mg daily | 0.6 mg daily |
| Maintenance Dose | 3.0 mg daily | 1.2 mg or 1.8 mg daily |
| Max Dose | 3.0 mg daily | 1.8 mg daily |
| Weight Loss (%) | 8% | 3.2% |
| A1C Reduction | N/A (not indicated for diabetes) | 1.1% |
| Key Trial | SCALE Obesity and Prediabetes (56 weeks) | LEADER (188 weeks) |
| List Price | $1,349/month | $950-$1,100/month |
| With Insurance | $25-$250/month (varies; weight-loss coverage is limited) | $25-$150/month (varies by plan) |
| Savings Card | $25/month (Novo Nordisk savings card, eligible patients) | $25/month (Novo Nordisk savings card, commercially insured) |
Side Effects: Saxenda vs Victoza
| Side Effect | Saxenda | Victoza |
|---|---|---|
| Nausea | 39% | 28% |
| Diarrhea | 21% | 17% |
| Constipation | 19% | 6% |
| Vomiting | 16% | 11% |
| Headache | 14% | 9% |
| Decreased appetite | 10% | 9% |
| Dyspepsia | 10% | 7% |
| Fatigue | 8% | Not reported |
| Dizziness | 7% | Not reported |
| Abdominal pain | 5% | Not reported |
| Pancreatitis (rare) | <1% | <1% |
| Gallbladder events | 2.5% | Not reported |
Severity scale: 1 (mild) to 5 (serious). Based on FDA prescribing information and clinical trial data.
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