Independent, evidence-based comparisons
Compare GLP-1
medications, side by side.
Ozempic vs Mounjaro. Wegovy vs Zepbound. Every GLP-1 drug pairing compared on efficacy, cost, side effects, and dosing — backed by FDA data and published clinical trials.
Ozempic
semaglutide
14.9%
body weight loss
Wegovy
semaglutide
16.9%
body weight loss
Mounjaro
tirzepatide
22.5%
body weight loss
Zepbound
tirzepatide
22.5%
body weight loss
Popular comparisons
The comparisons people
search the most.
Dual GIP/GLP-1 vs GLP-1 only
22.5%
Mounjaro
14.9%
Ozempic
Same ingredient, different label
T2 Diabetes
Ozempic
Weight loss
Wegovy
The weight loss head-to-head
16.9%
Wegovy
22.5%
Zepbound
Same drug, different approved use
Diabetes
Mounjaro
Weight + OSA
Zepbound
Active ingredient comparison
3 brands
Semaglutide
2 brands
Tirzepatide
Weekly GLP-1 for diabetes
14.9%
Ozempic
3.1%
Trulicity
All medications
Access a range of GLP-1 medications.
Ozempic
semaglutide
Novo Nordisk
14.9% weight loss
Wegovy
semaglutide
Novo Nordisk
16.9% weight loss
Mounjaro
tirzepatide
Eli Lilly
22.5% weight loss
Zepbound
tirzepatide
Eli Lilly
22.5% weight loss
Rybelsus
semaglutide
Novo Nordisk
4.4% weight loss
Trulicity
dulaglutide
Eli Lilly
3.1% weight loss
Saxenda
liraglutide
Novo Nordisk
8% weight loss
Victoza
liraglutide
Novo Nordisk
3.2% weight loss
Byetta
exenatide
AstraZeneca
2.8% weight loss
Bydureon BCise
exenatide extended-release
AstraZeneca
2.3% weight loss
Every comparison includes
Data you can actually trust.
Clinical efficacy
Weight loss percentages and A1C reduction from published trials like STEP, SURMOUNT, and SUSTAIN.
Side effects
Frequency rates with severity scoring from FDA prescribing information.
Cost breakdown
List price, insurance ranges, and manufacturer savings card details.
Dosing schedules
Starting dose, titration, maintenance, max dose, frequency, and route.
FDA approval
Approved indications, approval dates, label changes, and boxed warnings.
Editorial verdicts
Clear, cautious summaries of what the data shows for different use cases.
Sources: FDA prescribing information, NEJM, JAMA, Lancet, Diabetes Care
Ready to compare?
Find out how GLP-1 medications stack up against each other. Data-backed, independent, and free.
Browse all comparisonsThis content is for informational purposes only and is not medical advice. Always consult your healthcare provider before making medication decisions. See our full medical disclaimer.